Kate and Gerry McCann, whose three-year-old daughter vanished in Portugal nearly four years ago, were among hundreds running in London's Regent's Park in aid of the support group.

The two GPs, from Rothley, Leics, were accompanied by Peter Lawrence, father of missing York chef Claudia Lawrence and Rachel Elias, sister of Manic Street Preachers star Richey Edwards, who disappeared in 1995.

Kate said: "We are glad to help the charity continue to be a lifeline when someone disappears."